4. Trainspotting
While many people will argue that the British drug film Trainspotting is a comedy, and there are some laughter inducing moments, this is among the darkest, most profoundly disturbing comedies ever made. The film chronicles the lives of a group of heroin users in Edinburgh, Scotland. Ewan MacGregor plays Mark Renton, the main character, who struggles to get clean throughout.
Over the course of the story, a baby born to addicts dies of neglect, while neither the parents or their guests notice. A man fishes through a filthy toilet for a suppository, a man dies a horrible HIV/AIDS-related death, and Renton goes through a horrific bout of withdrawal after being locked in his bedroom by his parents.
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