2. Injections
If oral medications don’t work, a doctor might recommend injecting medication directly into the base or the side of the penis with a tiny needle or inserting a suppository into the urethra.
The injectable drug alprostadil is a synthetic version of prostaglandin E1, a hormone-like substance that functions similarly to ED pills. Some injections mix alprostadil with other medications—such as the vasodilator papaverine and the alpha-blocker phentolamine—to increase its effectiveness.
Your doctor can teach you to perform the injections yourself at home.
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