4. John McCain
If you thought that losing the presidential election was the toughest time in the life of John McCain, he has actually been through much worse. The former republican presidential candidate has been enduring a long battle with skin cancer and these medical troubles date all the way back to 1993. This man has been through so much: John McCain had four different melanomas by 2008, so obviously the election that year was not the most stressful situation he went through that year. The man has survived skin cancer several times over so losing the presidential election to Barack Obama was a cake walk in comparison.
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