2. Katherine Heigl
Katherine Heigl, star of Knocked up and Grey’s Anatomy, has a huge reputation for being one of the most difficult stars in Hollywood. Though there isn’t much talk about her these days, years back she often showed off her “tell it like it is” personality. While this may have earned some brownie points, her brutal honesty landed her in hot water numerous times, often at the expense of her successful acting career. Heigl had public disputes, most famously with her former bossShonda Rhimes. During her run on Grey’s, Heigl refused to accept an Emmy nomination for her role on the show. She eventually became too much to handle as she failed to show up promptly for work, forcing Rhimes to let her go. Since leaving Grey’s, Heigl has said she regrets her choice.
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